rai-lab

High Enhancer Activity is an Epigenetic Feature of HPV Negative Atypical Head and Neck Squamous Cell Carcinoma

Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine

Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy

Chromatin State Dynamics Confers Specific Therapeutic Strategies in Enhancer Subtypes of Colorectal Cancer

Enhancer reprogramming in PRC2-deficient malignant peripheral nerve sheath tumors induces a targetable de-differentiated state

Enhancer reprogramming confers dependence on glycolysis and IGF signaling in KMT2D mutant melanoma

Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells

Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-Throughput ChIP-sequencing in Tumor Tissues

Loss of histone acetylation and H3K4 methylation promotes melanocytic malignant transformation